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Consequential damages would be to see what the as mobile infantry. These adverse outcomes are usually associated with use of these drugs in the second and third trimester of pregnancy. Valsartan shows bi- exponential decay kinetics following intravenous administration, with an average elimination half-life of about 6 hours. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. (Calculations assume an oral dose of 320 mg/day and a 60-kg patient.) Hydrochlorothiazide: Two-year feeding studies in mice and rats conducted under the auspices of the National Toxicology Program (NTP) uncovered no evidence of a carcinogenic potential of hydrochlorothiazide. 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